SYBYL-X

SYBYL®-X 1.1 is the next generation and latest release of Tripos’ popular SYBYL® molecular modeling suite.  Released March 31, 2010 for Windows and Linux, SYBYL-X 1.1 is available as a software download to current customers.  A two-DVD set can be provided upon request.  Click here to request a media set. 

Enhancements in SYBYL-X 1.1 provide significant improvements in general usability, reducing by half the number of mouse clicks and by more than half the mouse travel needed for basic molecule visualization and manipulation, thereby providing a far more intuitive modeling experience.

Our overall goal while continuing development in SYBYL-X is to provide you with access to the highest quality and validated scientific techniques, so that application of CADD maximizes your productivity within an increasingly demanding working environment. We are working more closely with you to help us meet and exceed your goals for efficient accurate CADD.

The SYBYL-X strategy is three-fold:

• Quick Access - making the basic things quick and easy
• Workflows - simplifying and streamlining an entire workflow, from data input to presentation of results
• Scientific Innovation - creating and delivering scientific capabilities that provide the newest and/or best of those methodologies which are most helpful in the design of bioactive molecules.

SYBYL-X 1.1 leverages the major infrastructure investments we made in the first release of
SYBYL-X in late 2009, emphasizing Quick Access to make your use of SYBYL-X more efficient and pleasurable. You will notice many improved possibilities for the basic use of SYBYL-X.  Particularly noteworthy enhancements are:

• A new selection model that allows actions on selected entities
• Enhanced, simplified menu systems for frequently used functions
• Significantly updated toolbar system
• Context sensitive (right-click) menus
• Enhanced session saving capabilities

While the focus of this release has been Quick Access we have also made both workflow and scientific improvements:

Workflows:

Scientific improvements (in the updated Surflex-Dock version):

• Treatment of protein flexibility in docking
• Self-scoring term in docking scoring

To find out more about using Tripos' latest SYBYL release, please contact your local Sales Representative or email contact_us@tripos.com.