Fred Soltanshahi

Senior Technologist

Fred Soltanshahi worked as a business application analyst prior to joining Tripos in 1989. Fred has made contributions to a variety of Tripos products as member of the Polymer, SYBYL, NMR and UNITY groups. Fred contributed to novel methods for hi-D visualization/dimensionality reduction and partitioning large dataset. He was part of the team developing optisim signpost selection/partitioning software and PCA/NLM pipeline to reduce large dimensional space. He is currently working in the Informatics Research Center, collaborating with scientists to develop software for defining combinatorial virtual libraries, designing diverse subsets, 2 and 3D searching for similar compounds and analyzing the results.

Academics

BS Applied Mathematics and Computer Science, Southern Illinois University at Edwardsville, Edwardsville, Illinois, USA

Recent Publications

Balancing focused combinatorial libraries based on multiple GPCR ligands, F. Soltanshahi, T.E. Mansley, S. Choi & R.D. Clark; J. Comput.-Aided Molec. Design, 20, 529-538 (2006)  

OptDesign: Extending Optimizable k-Dissimilarity Selection to Combinatorial Library Design, Robert D. Clark, Julia Kar, Lakshmi Akella, Farhad Soltanshahi , Journal of Chemical Information and Computer Sciences, vol 42, 2003

Visualizing substructural fingerprints,Robert D. Clark, David E. Patterson, Farhad Soltanshahi, James F. Blake, and James B. Matthew, Journal of Molecular Graphics and Modeling, vol 18, 2000

Virtual Compound Libraries: A New Approach to Decision Making in Molecular Discovery Research, Richard D. Cramer, David E. Patterson, Robert D. Clark, Farhad Soltanshahi, Michael S. Lawless, Journal of Chemical Information and Computer Sciences, vol 38, 1998