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Home > Products > SYBYL-X

Reduced cost of ownership

No need for specialized hardware; use SYBYL on your platform of choice - Windows, Mac or Linux.

SYBYL-X 1.0 (Windows, Linux)
SYBYL 8.1.1 for (Mac)

SYBYL-X

Computational Informatics Software for Molecular Modelers

Straight Talk About Discovery Research
Whether you are looking for the next new breakthrough drug, the next generation in pesticides, the most exciting new flavor or fragrance, or any other molecular discovery project, we know what you’re up against. You have enormous pressure to produce results, in a very short period of time.

SYBYL®-X enables processes and decision-making that you control, not a onesize-fits-all confining approach. With SYBYL you look at molecular structures and properties in a manner that is designed to:

  • produce and optimize lead candidates
  • save time in your processes
  • smooth and simplify workflows
  • accelerate the pace of discovery

Functional Architecture
The key to SYBYL’s widespread use and acceptance in the scientific community is its simple but highly functional architecture.  The SYBYL Standard Base contains a powerful core of tools and functions designed to optimize, visualize and compare the attributes of molecular models and structures.  Two SYBYL Optional Base Modules, MOLCAD™ and Advanced Computation™, allow enhanced visualization capability, conformational searching and they facilitate unprecedented interoperability between and among other SYBYL application groups.  The SYBYL Applications are individually selected groups of computational chemistry and molecular modeling systems and tools tailored to accelerate and simplify the discovery process.

SYBYL Overview Brochure (2.23 MB)                    

SYBYL System Requirements

SYBYL image

The Problems Are Complex, but SYBYL-X Helps Make Things Easier

Ask yourself these few key questions:

  • Do I have a way to easily do molecular modeling that enables
  • structure building, optimization and comparison?
  • Can I quickly associate data with visualized structures?
  • How do I produce hardcopy and screen captures for information validation, sharing and exchange?
  • Do I have an efficient and proven technique for ligand-based design?
  • What about receptor-based design?
  • How will I handle building and manipulating protein structures?
  • Can I keep pace with the constant changes in computational informatics requirements, and insure a secure, up-to-date approach to my workflow?

Tripos understands that these are just a few of the issues you may face daily. If you haven’t investigated SYBYL-X you need to soon. The longer you put off consideration of Tripos’ solutions, the more difficult it will be to resolve problems that inevitably lie ahead. When you consider the number of organizations that have chosen SYBYL-X, you have to ask yourself what you may be missing.

  • SYBYL

SYBYL Base

Comprehensive tools for molecular modeling: structure building, optimization, and comparison; visualization of structures and associated data; annotation, hardcopy, and screen capture capabilities; and a wide range of force fields. With its easy-to-use interface, SYBYL Base is fully integrated with SYBYL Applications.

Ligand Based Design

Applications for SAR and ADME, as well as Pharmacophore Perception and Molecular Alignment

Receptor Based Design

Applications for Docking and de novo Design

Structural Biology

Applications for Macromolecular Modeling and Bioinformatics

Library Design

Applications for Library Creation and Molecular Diversity

Cheminformatics

Applications for Data Mining and Structure Representation

Supplemental Technologies

Applications for use in many computational informatics workflows